Introduction

A half billion are suffering from autoimmune diseases like irritable bowel disease, multiple sclerosis, Crone's disease, psoriasis, and fibromyalgia. Another half a billion people are suffering from depression and other mental illnesses. Indeed at least one person will have committed suicide by time you read this paragraph. (Hopefully, it won't be as result of reading this paragraph.) Instead, I believe this death will be due to massive failures in our current systems of clinical research and diagnosis. Currently, it costs as much as $48,000 per subject in a Phase III clinical trial. This has resulted in very little data on the effects of any factors that aren’t patentable.

Furthermore, something that most of these chronic conditions have in common is that is that they can be exacerbated or improved by hundreds of factors in daily life. They can be affected by the hundreds of chemicals you consume through your diet, treatments you've been prescribed, micro-nutrient intake, nutritional supplements, the amount of time spent in various sleep stages, the type, duration, and intensity of physical activity, social interaction, and even the weather!

Unfortunately, the human mind evolved to survive in a world without data millions of years ago on the African savannah. As a result it is only capable of holding 7 numbers in working memory at a time. Brains don’t have the bandwidth or statistical processing power required to analyze the massive amount of longitudinal data, time delays, and durations of action that has to be taken into account if we are to determine the likely influence of each of these factors on the individual’s symptoms.

The good news is that new devices and apps can automate the process of collecting all of this data and my brain can hold millions of numbers! I love to eat up all this data and analyze it determine which of these hundreds of factors have the strongest relationships the symptom or outcome of interest.

Your Data

Overall Mood Overview

Definitions

Review Column

Your puny human brains aren't worthless... yet. So it's best for you and your physician review the detailed analysis for each relationship and identify any issues such as:

• erroneous data
• missing data
• incorrect assumed duration of action
• incorrect assumed onset delay
• incorrect or missing ingredient tags

The Review column in each table is either marked as Verified, Unverified, or Erroneous. It links to a full analysis of the relationship. If it's Unverified, you can click it to review the data and make an assessment. If the analysis appears acceptable, click the Thumbs Up button in the study and it will be marked Verified on future reports. If the analysis appears flawed, either you can do one of the following:

• correct it within the app
• contact us at https://help.quantimo.do for assistance
• click the Thumbs Down button and it will be moved from this list to the Flagged Studies list in future reports

Confidence Column

This is just a subjective estimate of how seriously we may want to take the analysis based on several factors such as the amount of data available for the analysis.

Association Column

This shows the degree to which change seen in Overall Mood coincides with or is preceded by changes in a given variable.

Change Column

This is the typical amount of change seen in Overall Mood when a particular variable is above average relative to when it is below average. For example, if it says ↑10% in the Multivitamin column, it means that your Overall Mood is 30% higher after you take a Multivitamin. To be specific, this refers to the time during the specified duration of action following the onset delay following consumption of the vitamins. Conversely, if it says ↓10% in the Multivitamin column, it means that your Overall Mood is 30% higher after you take a Multivitamin (relative to the days when vitamins were not consumed).

RSD Column

RSD refers to the relative standard deviation of the Overall Mood measurements at baseline. Baseline refers to the outcome measurements taken when the predictor values in the preceding duration of action window were below average. For instance, if the predictor is a medication, this would refer to the period in which you were not taking the medication. If the absolute value of the change is more than the RSD, there is 68% chance that this change is not solely due to random fluctuation. If the absolute value of the change is more than twice the RSD, there is 95% chance that this change is not solely due to random fluctuation.

Baseline

Baseline refers to the outcome measurements taken when the predictor values in the preceding duration of action window were below average. For instance, if the predictor is a medication, this would refer to the period in which you were not taking the medication.

Correlation - The correlation coefficient represents is the degree to which change seen in Overall Mood coincides with changes in a given variable . The value can range from -1 to 1.

• Positive Correlation - The closer to 1, the more likely it is that above average values for the variable will coincide with ABOVE average Overall Mood.
• Negative Correlation - The closer to -1, the more likely it is that above average values for a particular variable will coincide with BELOW average Overall Mood.
• No Correlation - The closer to 0, the more likely it is that the variable and Overall Mood are not related.

Study Column

Click the Study link for any variable to see a more detailed analysis of the relationship.

Treatment-Related Factors

Treatment-Related Factors Predictive of Higher Overall Mood

Above average values of these treatments are usually followed by above average Overall Mood.

Each bar represents the amount of change seen in Overall Mood following above average values for that factor. Click to see the full study.

Predictor	Change	Predictive Coefficient	Data Points	Review	Outcome RSD at Baseline
Multivitamin	11.6%	0.244	192	Verified	24.4%
Memantine	4.6%	0.291	836	Verified	17.6%
B-Complex With Folic Acid Plus Vitamin C	10%	0.225	196	Verified	22.4%
Sundown Naturals Garlic	8%	0.226	236	Verified	21.2%
Probiotic Plus	12.1%	0.337	135	Verified	17.6%
Iberogast (mL)	2.4%	0.176	246	Verified	8.1%
Berberine Plus By Nova Nutrition	3.7%	0.151	368	Verified	13.7%
Chelated Zinc	3%	0.139	913	Verified	13.5%
Mouth Gaurd	2.7%	0.169	200	Verified	12.1%
Alphalipoic Acid	10%	0.196	188	Verified	20.4%
Berberine	3.4%	0.106	1958	Verified	14.6%
Omega 3 Fatty Acids	7.1%	0.072	2130	Verified	16.7%
Melatonin (mg)	5.8%	0.03	2216	Verified	16%
Nature's Bounty Zinc	3.1%	0.086	535	Verified	17.3%
Opti-Men Multivitamin (count)	1.7%	0.083	1245	Verified	15.3%
Optimized Folate By Life Extension	9.3%	0.415	91	Verified	10.7%
Green Tea By Finest Nutrition	9.8%	0.492	62	Verified	11.5%
Vitamin D3 By NatureMade	5.1%	0.117	267	Verified	18.2%
Polyethylene Glycol 3350	7%	0.174	155	Verified	19.6%
SAM-E 400 (tablets)	8.1%	0.273	97	Verified	15.4%
Optimum Nutrition Micronized Creatine Monohydrate Powder	2%	0.071	254	Verified	13.8%
Zinc	0.4%	0.058	1958	Verified	13%
DenTek Extra Strong Triple Clean Floss Picks (count)	1.4%	0.061	580	Verified	17.4%
L-Glutamine By Body Fortress	1.4%	0.065	267	Verified	13.6%
Reservatrol Plus	3.1%	0.153	121	Verified	17.4%
Purelife Energy Boost	3.4%	0.135	121	Verified	17.2%
Humira (units)	12.6%	0.261	197	Verified	23.1%
Magnesium Citrate By Now (count)	4.8%	0.237	35	Verified	19%
Garlic (Count)	2.5%	0.121	95	Verified	10.7%
Glutamine (Count)	3.3%	0.056	194	Verified	13.4%
Source Naturals Vitamin D-3	1.2%	0.045	430	Verified	17.5%
Jdtic	6.7%	0.081	152	Verified	19.6%
L-Glutamine	0.7%	0.03	1961	Verified	13.5%
LSD-P Microdose	5.4%	0.113	325	Verified	17.7%
Grapefruit Seed Extract (GSE)	1.7%	0.03	258	Verified	8.3%
Inulin	1.5%	0.032	2009	Verified	14.6%
UVB	8.7%	0.155	368	Verified	12.9%
Super Omega-3	1.6%	0.026	161	Verified	17.9%
Zoloft	8.6%	0.379	72	Verified	12.7%
Creatine Fuel Stack	6.8%	0.134	57	Verified	22.5%
Theanine Serene With Relora And GABA	-2.4%	0.012	209	Verified	14.4%
Kefir By Lifeway	0.3%	0.002	1375	Verified	12.3%
Probiotics (pills)	-0.1%	0.012	111	Verified	15%
Inositol & Choline By Source Naturals	2.8%	0.077	78	Verified	15.7%
Sundown Naturals Odorless Garlic	-0.2%	0.003	575	Verified	15.5%

Treatment-Related Factors Predictive of Lower Overall Mood

Above average values of these treatments are usually followed by below average Overall Mood

Each bar represents the amount of change seen in Overall Mood following above average values for that factor. Click to see the full study.

Predictor	Change	Predictive Coefficient	Data Points	Review	Outcome RSD at Baseline
Deprenyl	-12.2%	-0.298	1437	Verified	17.7%
Deprenyl (Selegiline)	-12.2%	-0.298	1437	Verified	17.7%
5 HTP	-15.9%	-0.227	577	Verified	26.3%
Super B Complex	-8.9%	-0.322	1005	Verified	12.9%
Nova Nutritions Acetyl L-Carnitine	-9.1%	-0.244	187	Verified	2.9%
Therapeutic M Multivitamin	-10.4%	-0.334	142	Verified	21.5%
Optimum Omega 3 Fish Oil	-3.9%	-0.167	825	Verified	12.1%
Glycerin Vegetable Kosher USP-Highest Quality Available-1 Quart	-15.9%	-0.634	131	Verified	7.7%
Digestive Advantage Probiotic	-3.1%	-0.138	887	Verified	9.8%
Opti-Men	-6.5%	-0.181	335	Verified	14.1%
Pro-Biotics Plus	-4%	-0.222	93	Verified	13.7%
Vitamin D3	-4.6%	-0.093	1685	Verified	12.7%
Earths Pearl Probiotic	-1.5%	-0.213	493	Verified	9.8%
Vinpocetine	-4.4%	-0.177	128	Verified	24.1%
Mirtazapine	-2.8%	-0.086	2163	Verified	19.2%
Acetyl-L-Carnitine	-2.5%	-0.071	2193	Verified	14.8%
Wellbutrin	1.1%	-0.017	2216	Verified	17.1%
Meditation	-1%	-0.039	1758	Verified	12.6%
Cranial Electro Stimulation	-15.5%	-0.225	110	Verified	19.3%
Folic Acid By Solaray	-2.4%	-0.107	118	Verified	9.5%
Cold Shower (min)	-1.5%	-0.057	868	Verified	13.2%
Cosentyx	-1.9%	-0.086	1185	Verified	12.4%
Opti-men Multivitamin	-4.9%	-0.193	65	Verified	10.2%
Turkish Honey Vape E-cigarette Juice	-1%	-0.055	238	Verified	9.5%
Mirtazipine Powder	-1.2%	-0.048	2163	Verified	19.2%
Harmala/Harmaline FB Oral	-3.4%	-0.097	173	Verified	18.2%
Clobetasol Propionate Cream 0.05%	-0.7%	-0.046	1531	Verified	12%
Remeron	-2.2%	-0.042	2163	Verified	19%
DMT Smoked	-3.1%	-0.046	509	Verified	14.6%
TDCS F3/FP2	-1.9%	-0.057	314	Verified	10.5%
Melatonin (Weight)	-3.3%	-0.063	1259	Verified	12%
Berberine Plus By Best Naturals	-0.8%	-0.028	1020	Verified	11%
Inositol	-6.5%	-0.167	87	Verified	13.6%
Listerine Antiseptic Mouthwash	-2.7%	-0.027	580	Verified	14.8%
Ketamine	-1.3%	-0.16	132	Verified	20%
Kinky E-Cig Vape Juice	1.3%	-0.01	259	Verified	10.5%
Melatonin	-1.1%	-0.045	62	Verified	13.1%
NSI-189	0.4%	-0.052	56	Verified	12.8%
LSD	-7.6%	-0.061	1236	Verified	20.4%
Marijuana	-0.8%	-0.04	129	Verified	7.3%
Methotrexate (mg)	-1%	-0.04	118	Verified	13.3%

Un-Reviewed Studies of Treatment-Related Factors

Please click the Unverified link to view these studies to view and then click:

• thumbs up to indicate the ones that you feel are valid
• thumbs down to indicate the ones that you feel are flawed in some way

Each bar represents the amount of change seen in Overall Mood following above average values for that factor. Click to see the full study.